Omics · study · 2026
Inhibition of fatty acid binding protein 4 alleviates psoriasis-like skin inflammation by modulating macrophage polarization
Listed in NCBI GEO
This study provides single-cell RNA-seq profiles of human psoriasis lesional skin samples generated using the 10x Genomics single-cell platform.
Description
Human skin biopsies were dissociated into single-cell suspensions and processed for 10x Genomics 5' single-cell RNA-seq. Processed data include filtered feature-barcode matrices containing raw UMI counts.
For SNP-multiplexed libraries, barcode-level sample assignment was performed using Demuxalot, and Demuxalot assignment files are provided together with the processed count matrices. These data enable cell-type-level analysis of immune and stromal cell populations in human psoriasis skin.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337821 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337821 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1491188 ncbi.nlm.nih.gov/bioproject/PRJNA1491188 ↗
project · from NCBI GEO
- PubMed 42609463 pubmed.ncbi.nlm.nih.gov/42609463 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE337821 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |