Omics · study · 2026
An atlas of genetic effects on the monocyte methylome across European and African populations
Listed in NCBI GEO
This study investigates the genetic regulation of DNA methylation in purified human monocytes across African American and European American populations.
Description
Whole-genome bisulfite sequencing (WGBS) and whole-genome sequencing (WGS) were performed on participants from the Louisiana Osteoporosis Study cohort to characterize methylation quantitative trait loci (meQTLs), heritability patterns, and methylome-wide associations with complex traits.
The study provides a comprehensive multi-ancestry monocyte methylome atlas.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE324nnn/GSE324619 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE324619 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1436207 ncbi.nlm.nih.gov/bioproject/PRJNA1436207 ↗
project · from NCBI GEO
- PubMed 41904542 pubmed.ncbi.nlm.nih.gov/41904542 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Methylation profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- Epigenetics 75% · Genome sequencing 65% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE324619 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:field:310504 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:methylation-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:genome-sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |