Data · dataset · 2025
Data for: Tumor evolution and immune microenvironment dynamics in primary and relapsed mantle cell lymphoma
Listed in Researchdata.se
Data availability This dataset can only be shared within Sweden due to legal restrictions.
Description
Abstract
Mantle cell lymphoma (MCL) is a rare but often aggressive type of B-cell lymphoma with a high risk of relapse. To understand the mechanisms driving disease relapse, we employed single-cell RNA sequencing (scRNAseq) in 20 samples from diagnosed/untreated (primary, n = 11) and/or relapsed tumors (n = 9) from 11 MCL patients. Whole-genome sequencing was also performed on the available samples.
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The total size of the deposited data is approximately 1.3 TB. It contains 70 GNU zipped fastq files with raw data and one documentation file in xlsx format. All fastq file names are included in the documentation file metadata.xlsx.
Links
Where it is published
- DOI doi.org/10.48723/kfy8-5r05 ↗
DOI / persistent id · from researchdata se
Catalogue records · 1
- OAI-PMH record api.researchdata.se/oai-pmh?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3A… ↗
metadata API · from researchdata se
Topics
- From keywords
- Earth & Environmental Science · Life Sciences · Medicine & Health
- Inferred from text
- Cancer 65% · Disease 75% · Genome sequencing 65% · Oncology and carcinogenesis 72% · RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 75%
Provenance · 1 source records, 16 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Researchdata.se | oai:researchdata.se:2024-497/1 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata se | connector:researchdata_se@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[disease].local:disease:disease | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3211 | enrichment · researchdata se | taxonomy-embedding@1.1.0 | title+keywords+description (72%) |
| concepts[field].local:field:earth-environmental | mapping · researchdata se | connector:researchdata_se@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata se | connector:researchdata_se@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata se | connector:researchdata_se@1.0.0 | |
| concepts[modality].local:modality:genome-sequencing | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:rna-seq | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · researchdata se | connector:researchdata_se@1.0.0 | /metadata/dc/description |
| license_text | source · researchdata se | connector:researchdata_se@1.0.0 | |
| publication_date | source · researchdata se | connector:researchdata_se@1.0.0 | |
| spatial | source · researchdata se | connector:researchdata_se@1.0.0 | |
| title | source · researchdata se | connector:researchdata_se@1.0.0 | /metadata/dc/title |