Omics · study · 2026
Parallel single-cell host immune pro ling and pathogen genomic characterization in Klebsiella- associated sepsis: a pilot study
Listed in NCBI GEO
This study employed a single-cell RNA sequencing approach using 10x Genomics scRNA-seq to investigate peripheral blood immune responses in sepsis.
Description
Peripheral blood mononuclear cells (PBMCs) were collected from adult patients with sepsis associated with Enterobacterales bloodstream infection and from healthy controls. The study was designed to characterize the single-cell immune profile of sepsis and to compare PBMC transcriptional profiles between septic patients and healthy subjects.
Processed Cell Ranger raw/unfiltered and filtered feature-barcode matrices are provided for each sample.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE333nnn/GSE333704 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE333704 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1472075 ncbi.nlm.nih.gov/bioproject/PRJNA1472075 ↗
project · from NCBI GEO
- PubMed 42656611 pubmed.ncbi.nlm.nih.gov/42656611 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Genetics 70% · RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 75%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE333704 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (70%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |