Omics · study · 2026
Single-cell RNA sequencing of primary cultures of neonatal digit amputation wound cells 4 days post-amputation and treated with FGF2 for 24H
Listed in NCBI GEO
Primary wound cells were isolated and treated with FGF2 (100 ng/ml) for 24 hours, and analyzed by single cell RNA sequencing (scRNAseq).
Description
The dataset from FGF2 treated wound fibroblasts was compared to our previously published dataset for un-treated primary wound cells(GSE185197) to determine the transcriptomic changes in treated fibroblasts. We found Hmga1 and Hmga2 as novel FGF2-inducible genes potentially linked to fibroblast dedifferentiation during FGF2 induced blastema formation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE297nnn/GSE297901 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE297901 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1266696 ncbi.nlm.nih.gov/bioproject/PRJNA1266696 ↗
project · from NCBI GEO
- PubMed 41997949 pubmed.ncbi.nlm.nih.gov/41997949 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE297901 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |