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Omics · study · 2026

The effects of the hepatocyte targeted RSPO mimetic, SZN-043, on liver cells

Listed in NCBI GEO

We assessed the effects on liver cells of repeated dosing the hepatocyte targeted RSPO mimetic, SZN-043, on liver cells by applying scRNA-seq to dissociated liver cells at 24-hours after one dose, 24-hours after 14 consecutive daily doses, and upon a 2-month washout.

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Life Sciences
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Single-cell RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29417312 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:single-cell-rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title