Data · dataset · 2025
Single-cell multimodal sequencing data from: Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Listed in Researchdata.se and Swedish National Data Service — shown once because both records carry DOI 10.17044/scilifelab.23592270
This dataset contains single-cell multimodal data (scRNA-, scBCR-, and scADT-seq) for twenty-three cases of childhood BCP-ALL, including four samples each of BCR::ABL1-positive, ETV6::RUNX1-positive, and HeH, together with eleven samples of DUX4-rearranged ALL.
Description
In addition, the datset contains 9 samples of mononuclear cells, sorted CD34+ (n=3), CD19+ (n=3), and unsorted (n=3), from five normal bone marrow from healthy donors.
The dataset is available as raw sequencing reads (fastq; restricted access) or as an annotated multimodal dataset (h5ad). Cells from bone marrow were used for single-cell library preparation, according to the manufacturer’s protocol (10X Genomics CG000208: Chromium Next GEM Single Cell V(D)J Reagent Kits v1.1). The libaries were sequenced on a Novaseq 6000.
Links
Where it is published
- DOI doi.org/10.17044/scilifelab.23592270 ↗
DOI / persistent id · from researchdata se
Catalogue records · 2
- OAI-PMH record api.researchdata.se/oai-pmh?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3A… ↗
metadata API · from researchdata se
- OAI-PMH record snd.se/oai-pmh?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3A… ↗
metadata API · from snd se
Topics
- From keywords
- Earth & Environmental Science · Earth & Environmental Science · Medicine & Health · Medicine & Health
- Inferred from text
- Oncology and carcinogenesis 73% · Sequencing 75%
Related
Provenance · 2 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Researchdata.se | oai:researchdata.se:doi-10-17044-scilifelab-23592270/0 | 13 d ago | JSON v1 |
| Swedish National Data Service | oai:researchdata.se:doi-10-17044-scilifelab-23592270/0 | 2 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].anzsrc:group:3211 | enrichment · researchdata se | taxonomy-embedding@1.1.0 | title+keywords+description (73%) |
| concepts[field].local:field:earth-environmental | mapping · researchdata se | connector:researchdata_se@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · snd se | connector:snd_se@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata se | connector:researchdata_se@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · snd se | connector:snd_se@1.0.0 | |
| concepts[modality].local:modality:sequencing | enrichment · researchdata se | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · researchdata se | connector:researchdata_se@1.0.0 | /metadata/dc/description |
| license_text | source · researchdata se | connector:researchdata_se@1.0.0 | |
| publication_date | source · researchdata se | connector:researchdata_se@1.0.0 | |
| title | source · researchdata se | connector:researchdata_se@1.0.0 | /metadata/dc/title |