Omics · study · 2026
Single-cell RNA-sequencing of CD34 lineage cells from aortic allografts of mouse models
Listed in NCBI GEO
The role of CD34 lineage cells in aortic allografts remains unintelligible.
Description
To characterize the CD34 lineage cells in aortic allografts, Cd34-CreERT2 mice were crossed with Rosa26-tdTomato mice to generate Cd34-CreERT2; Rosa26-tdTomato mice and label CD34 lineage cells in mice. We further performed single-cell RNA sequencing of whole remodeled vessel cells from Cd34-CreERT2; Rosa26-tdTomato mice with a murine model of aortic allograft (AG) at an early (AG 2w) and late stage (AG 4w).
The single-cell RNA-seq analyses revealed the heterogeneity of CD34 lineage cells in vascular remodeling.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE268nnn/GSE268529 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE268529 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1117519 ncbi.nlm.nih.gov/bioproject/PRJNA1117519 ↗
project · from NCBI GEO
- PubMed 42549511 pubmed.ncbi.nlm.nih.gov/42549511 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE268529 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |