253 datasets

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<p>Bulk fermentation of cigar tobacco leaves couples microbial succession and chemical transformations; however, it remains unclear whether commercially distinct filler and wrapper leaves follow different ecological and biochemical trajectories under identical industrial conditions. Using 16S rRNA and ITS amplicon sequencing, together with conventional chemical indices and volatile profiling, we t

ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset · unknown

Foldamers are artificial oligomers that utilise a range of non-covalent interactions to adopt well-defined conformations akin to the secondary and occasionally tertiary structures of biomacromolecules. With this mimicry, foldamers are therefore seen as a potential platform to replicate the vast array of functions that biomacromolecules perform such as molecular recognition, catalysis, and signalli

ZivaHub + Deakin Research Online + DMU Figshare + UCL Research Data Repository2026 · dataset · unknown

Many Iron-containing hydroxylases have a high degree of regio- and diastereoselectivity and can be used as biocatalysts for producing specific chiral alcohols from un-active C-H sites. Here C-H functionalization catalyzed by Iron-containing heme and nonheme were studied, using cytochrome P450 and PtlH as examples. In this work, the C-H activation in the hydroxylation reaction of a model substrate

ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<h3 dir="ltr"><b><u>DESCRIPTION</u></b></h3><p dir="ltr">Presented are OASIS and GDSII Design Files for the TypeOneBIS Biogenic Replicator -- <b>a programmable universal molecular constructor</b> -- that assembles sequence-defined molecules from user provided digital molecular sequence files, using a logarithmic hierarchical merge matrix.</p><p dir="ltr">This dataset contains the complete mask lay

ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset · unknown

Using Nature as divine inspiration, we looked towards synthesising unnatural, man-made foldamers. These molecules are able to adopt a well-defined structure, capable or replicating or selectively inhibiting some of Nature’s most important biological interactions. Chapter 1: Introduces the concept of foldamers and how they relate to peptide secondary and tertiary structure. This chapter will be foc

ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset · unknown

The primary objective of this thesis was to examine whether specific amino acid alterations in a well-established cell-penetrating peptide used to form nanoparticles, RALA, improve or hinder the performance in the delivery of nucleic acids. The alterations were based on substituting amino acid residues in the peptide, with respect to side-chain length, the potential for disulphide linkage between

ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset

The emerging technology of microfluidics is used here in this thesis to encapsulate both biologic and small molecule active pharmaceutical ingredients within lipid-based nanoformulations. A focus on the use of additive manufacturing for the fabrication of microfluidic devices is given, with analysis into the effect of device parameters on the properties of the final nanoformulation. Using these pr

ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset · unknown

Rapid depletion of fossil fuel stock with a simultaneous rise in greenhouse gas emissions has led to an increase in the need for alternative energy. Cellulose based biofuels, especially bioethanol is a form of alternative energy that has the potential to replace petrol. The first step in cellulosic bioethanol production is the release of fermentable sugars via pre-treatment. Conventionally, physic

UCL Research Data Repository2026 · dataset · unknown

The cis¬-dihydrodiol compounds, produced by the highly regio- and stereo-selective Rieske non-heme iron oxygenases, such as toluene dioxygenase (TDO), are versatile synthons for chiral, asymmetric synthesis. The cis-dihydroxylation of ortho- and meta-substituted phenols by TDO produce cyclohexenone cis-diols. The keto group of cyclohexenone cis¬-diol tautomers increases the functionalisation and s

ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset

<p>This thesis explores the use of condensed tannins from willow leaves (Salix spp.) as a sustainable dietary supplement for ruminants to reduce methane emissions and improve nitrogen use efficiency. Willow leaves, abundant across Europe, offers high protein and moderate energy levels, making it a useful feed source. The research aimed to evaluate the inclusion of willow leaves to potentially miti

ZivaHub + Deakin Research Online + DMU Figshare + UCL Research Data Repository2026 · dataset

Nanotechnology is one of the most exciting and fast-moving areas of science today. A wide range of medical applications use nanoscale materials in the diagnosis, treatment, and prevention of various diseases. Nanoparticles (NPs) are being extensively studied as drug delivery systems due to their ability to minimize toxicity and improve efficacy. Poly lactic-glycolic acid is one of the most commonl

ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset

Achieving deterministic control over molecular recognition at high-curvature bio-nano interfaces remains a fundamental challenge. For two decades, DNA-mediated single-wall carbon nanotube (SWCNT) sorting has relied on empirical screening, leaving the underlying recognition code largely undeciphered. Here, we report a <i>de novo</i> design framework that rationally programs DNA sequences via a gene

ZivaHub + HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">This dataset contains compositional and biochemical measurements of prairie biomass collected to evaluate the native grassland species as feedstocks for anaerobic digestion. Biomass from 14 prairie species, including grasses and forbs, was sampled from three sites in Iowa and Missouri across two harvest periods (summer and fall). The dataset includes results from biochemical methane p

HKU DataHub + figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This release provides cleaned, analysis-ready CSV files digitized from industrial baker’s-yeast (<i>Saccharomyces</i>) fed-batch fermentation PDF batch logs. The PDF sheets were completed by experienced plant operators and technicians based on on-site measurements and observations during production. Original PDF sheets are not redistributed with this package. The dataset supports rese

ScienceDB2026 · dataset · restricted

Myceliophthora thermophila is a thermophilic filamentous fungus with great potential for biomass biorefining and industrial protein production. Lignocellulolytic enzyme production in this fungus is governed by regulatory networks that integrate environmental sensing, transcriptional regulation, and protein secretion. However, the locus-specific epigenetic control of these networks remains poorly u

NCBI GEO2026 · Genome binding/occupancy profiling by high throughput sequencing · 18 samples

Precise and rapid control over cellular protein levels is essential to dissect complex biological systems. Chemical genetic approaches such as dTAG, in which a target is fused to a degron tag (FKBP12F36V) and degraded upon small molecule-mediated recruitment of E3 ligases, have enabled rapid and tunable control over protein abundance. However, no analogous tool exists to precisely increase protein

ScienceDB2026 · dataset · restricted

l-Glutamic acid is conventionally produced by bacteria from starch-derived sugar while its production in eukaryotic hosts remains rarely reported. The thermophilic ascomycete fungus Myceliophthora thermophila has been developed as a platform for producing value-added chemicals from lignocellulosic biomass. In this study, we explored the feasibility of engineering M. thermophila for l-glutamate pro

ScienceDB2026 · dataset · restricted

Microbial biotransformation presents a sustainable strategy for mitigating global microplastics (MPs) pollution but is fundamentally constrained by the difficulty to directly identify and recover functionally active MPs-transforming microorganisms from complex microbial communities. Here, we established a function-driven, single-cell Raman spectroscopic framework that integrated deuterium-based me

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p>β-1,3-glucan from Euglena gracilis is an emerging microalgal prebiotic. However, its potential to reprogram the metabolic profile of lactic acid bacteria has not been reported previously. In the present study, the effects of insoluble β-1,3-glucan on growth dynamics, gene expression, and the extracellular metabolite profile of Lactococcus lactis DSM20175 were investigated using transcriptomic a

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p>Bacterial pigments have broad industrial applications and are relatively easy to scale up. However, Arctic microbial sources remain largely unexplored. In this study, we isolated a yellow-pigmented bacterium, PS104, from the Arctic Ny-Ålesund fjord in Kongsfjorden, Svalbard, Norway. Biochemical assays and 16S rRNA gene sequencing revealed that PS104 is closely related to the genus Citricoccus.

NCBI GEO2026 · RNA sequencing · 5 samples

While pluripotent stem cell-based therapy hold great promises to treat skin injuries, one of the current challenges for industrial bioproduction is the development of non destructive in-process quality control. In this study, we present a new and original methodology capable to identify specific temporal biomarkers of keratinocytes differentiation. To do so we combined unbiased single-cell RNA seq

figshare + Loughborough Research Repository2026 · RNA sequencing

<p dir="ltr">This dataset contains the processed data supporting the findings of the accompanying manuscript on pasteurized <i>Akkermansia muciniphila</i> 11 (pAKK11) treatment in a mouse model of diabetes. It includes: gut microbiome relative abundance (phylum and genus level), short-chain fatty acid (SCFA) quantification, transcriptomic analyses (GSVA and differentially expressed genes), and pro

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p>Bacteriocins are ribosomally synthesized antimicrobial peptides with promising applications in biotechnology, particularly in food preservation and animal and human health. Circular bacteriocins are especially attractive due to their head-to-tail cyclized structure, which confers enhanced stability and antimicrobial potency relative to linear peptides. Here, we report an in vitro cell-free prot

Edmond2026 · Astronomical catalogue · unknown

In this dataset you find plasmid sequences utilized for succinate production in Escherichia coli in genebank (gb) format under plasmids/. Furthermore, you find a stochiometric metabolic model of a succinate producing E. colistrain, meant to be viewed via the CellNetAnalyzer software (https://github.com/cnapy-org/CNApy), as well as scenarios that can be used for this model under FBA_and_MFA_calcula

figshare2026 · Astronomical catalogue

<p dir="ltr">This dataset contains the supporting data for the manuscript “[A red-light-activated multimetallic nanocomposite promotes bacterial killing and macrophage activation]”. It includes [individual measurements underlying the figures and statistical analyses, original experimental images, and transcriptomic analysis results]. Files and worksheets are labelled by figure and panel number to