21 datasets

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing

<p dir="ltr">Seurat object (Filtered, processed scRNA-seq data) from Sakimoto et al, BJC Reports, 2024 (https://doi.org/10.1038/s44276-024-00112-3).</p>

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">Nuclei Isolation was performed according to 10X Genomics demonstrated protocol (Nuclei Isolation for Single Cell Multiome ATAC + Gene Expression Sequencing - CG000365) starting with 5x10⁵ fresh cells. Cells were incubated with the lysis buffer for 4 minutes. Single-nuclei ATAC and 3’ gene expression sequencing libraries were generated using the Chromium Next GEM Single Cell

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">5,000 CD45⁺ or CD45^neg sorted cells from cryopreserved distal normal lung or lung adenocarcinoma of 4 male donors were pooled and loaded per well of the Chromium Next GEM Chip G (10X Genomics) and loaded into the 10X Genomics Chromium controller according to the manufacturer’s protocol. Reverse transcription, cDNA amplification, and the subsequent library prepara

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">CyTOF data underwent the following pre-processing prior to analyses: First, the CyTOF software by Fluidigm was used for normalization and concatenation of the acquired data. Then, several gates were applied using the FlowJo platform:</p><p dir="ltr">Live single cells were gated using the cisplatin 195Pt and iridium DNA label in 191Ir. Next, the normalization beads were gated out using

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">CyTOF data underwent the following pre-processing prior to analyses: First, the CyTOF software by Fluidigm was used for normalization and concatenation of the acquired data. Then, several gates were applied using the Cytobank platform (Beckman Coulter):</p><p dir="ltr">First, the normalization beads were gated out using the 140Ce channel. Then, live single cells were gated using the c

HKU DataHub + figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">Gastric cancer (GC) remains a major cause of cancer-related mortality, and the mechanisms that preserve oncogenic protein stability remain incompletely understood. Here, we identify myeloid leukemia factor 2 (MLF2) as an oncogenic proteostatic regulator that protects KLF5 from ubiquitin-dependent degradation in GC. Analysis of TCGA datasets showed that MLF2 was upregulated in GC tissu

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p>Cancer-associated cadherin 20 (CDH20) is a novel identified cadherin that is genetically altered in several types of human cancer, including cervical cancer. However, its involvement in the progression of cervical cancer remains unknown. In this study, we show that CDH20 was downregulated in clinical cervical cancer samples and its expression correlated with cervical cancer clinical features. C

figshare + Loughborough Research Repository2026 · Astronomical catalogue

Background<p>The survival for many children with relapsed/refractory cancers remains poor despite advances in therapies. Arginine metabolism plays a key role in the pathophysiology of a number of pediatric cancers. We report the first in child study of a recombinant human arginase, BCT-100, in children with relapsed/refractory hematological, solid or CNS cancers.</p>Procedure<p>PARC was a single a

figshare + Loughborough Research Repository2026 · Astronomical catalogue · restricted

<p dir="ltr">The dataset contains the raw data and processed data presentation of the research"Deciphering the Putative Cell-of-Origin and Cuproptosis-Based Therapeutic Vulnerabilities of Ovarian Clear Cell Carcinoma". The content includes the in vitro experimental assays such as cell proliferation assay, flow cytomety, IHC staining, western blot etc and in vivo experiment records.</p>

figshare2026 · Astronomical catalogue

<p dir="ltr">Raw expression data and clinical data of TCGA-CRC</p>

figshare2026 · Astronomical catalogue

<h2 dir="ltr">Sequence raw data of GSE161277.</h2><p></p>

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

<p dir="ltr">Analysis code, derived data and results accompanying the study "Early-onset and late-onset</p><p dir="ltr">colorectal cancer differ by a graded transcriptional shift rather than a discrete regulatory</p><p dir="ltr">state" (Desterke, Yu & Mata-Garrido).</p><p><br></p><p dir="ltr">The study reassesses whether a 15-gene CBX3-associated programme separates early-onset (EOCRC)</p><p dir="

figshare2026 · Astronomical catalogue

<p dir="ltr">KRAS, BRCA, and TP53 Mutations as Prognostic Biomarkers in Pancreatic Cancer: A Systematic Review and Meta-Analysis</p><p dir="ltr"><b>1. General Information</b></p><ul><li>Study Title: KRAS, BRCA, and TP53 Mutations as Prognostic Biomarkers in Pancreatic Cancer: A Systematic Review and Meta-Analysis of Survival Outcomes</li><li><b>Corresponding Author:</b> Wahby Mohammed Babaresh</li

NCL Data2026 · dataset

<p dir="ltr">This draft repository contains supplementary data described in the draft manuscript - <b>Genomic Entropy confers an aggressive Phenotype in Mesothelioma, </b>manuscript in presubmission stage. The data includes somatic mutations (text files) obtained from whole-exome sequence analysis of 277 mesotheliomas and analysed using phylogenetic methods to infer the genetic evolution of mesoth

ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">This draft repository contains supplementary data described in the draft manuscript - <b>Genomic Entropy confers an aggressive Phenotype in Mesothelioma, </b>manuscript in presubmission stage. The data includes somatic mutations (text files) obtained from whole-exome sequence analysis of 277 mesotheliomas and analysed using phylogenetic methods to infer the genetic evolution of mesoth

DataCite2025 · dataset

1. figs.Rmd contains code that generated all figures except for the panel signature figure (Fig. 2) 2. panel.Rmd contains code for the panel sig figure (Fig. 2)

Teesside University Research Data Repository2018 · dataset

Large-scale cancer sequencing studies of patient cohorts have statistically implicated many cancer driver genes, with a long-tail of infrequently mutated genes. Here we present CHASMplus, a computational method to predict driver missense mutations, which is uniquely powered to identify rare driver mutations within the long-tail. We show that it substantially outperforms comparable methods across a