60 datasets

NCBI GEO2026 · Non-coding RNA profiling by array · 68 samples

microRNA signatures with diagnosis, distant metastasis and prognosis for nasopharyngeal carcinoma

NCBI GEO2026 · Non-coding RNA profiling by array · 115 samples

This SuperSeries is composed of the SubSeries listed below.

NCBI GEO2026 · Non-coding RNA profiling by array · 32 samples

In this study, we introduce a data-comprehensive human B-cell cancer cell line (HBCCL) panel comprising 17 diffuse large B-cell lymphoma (DLBCL) cell lines and 18 multiple myeloma (MM) cell lines. The panel includes integrated datasets from drug dose–response screens (11 agents), gene expression profiling, and quantitative proteomics. The utility of this resource is illustrated with examples of an

NCBI GEO2026 · Non-coding RNA profiling by array · 24 samples

Astrocytes are critical regulators of central nervous system homeostasis and responses to viral infection, yet how the extracellular environment shapes astrocyte susceptibility to neurotropic viruses remains poorly understood. Here, we investigated the temporal and molecular consequences of human coronavirus 229E (HCoV-229E) infection in primary human astrocytes using integrated virological, ultra

NCBI GEO2026 · Non-coding RNA profiling by array · 6 samples

Circular RNAs (circRNAs) are stable, tissue- and developmental-stage-specific regulators of gene expression and candidate disease biomarkers. Their expression profile in abnormal lung development in congenital diaphragmatic hernia (CDH) is unknown. To evaluate circRNA expression profile in CDH-associated abnormal lung development. We profiled circRNAs in rat CDH and control lungs at embryonic day

NCBI GEO2026 · Non-coding RNA profiling by array · 1 samples

We used Xenium In Situ assay with a custom probe panel to visualize a human bladder cross-section. The custom probe panel contains probe sets against bladder cell type marker genes and RNA isoforms to enable cell identification. We detected 30 distinct cell groups consisted of urothelial cell states, immune cells, and various stromal cell types.

NCBI GEO2026 · Excel spreadsheet · 6 samples

Circular RNAs (circRNAs) are stable, tissue- and developmental-stage-specific regulators of gene expression and candidate disease biomarkers. Their expression profile in abnormal lung development in congenital diaphragmatic hernia (CDH) is unknown. To evaluate circRNA expression profile in CDH-associated abnormal lung development. We profiled circRNAs in rat CDH and control lungs at embryonic day

NCBI GEO2026 · Non-coding RNA profiling by array · 18 samples

miRNA profiling of prostate cancer cell lines was performed using GeneChip™ miRNA 4.0 Arrays (Affymetrix, Santa Clara, CA, US).

NCBI GEO2026 · Non-coding RNA profiling by array · 9 samples

The ACTB gene, traditionally considered a reference gene, exhibits transcriptional instability in colorectal cancer tissues. The aim of this study was to evaluate the transcriptomic profile of colorectal adenocarcinoma, with a specific focus on structural genes and their regulatory networks within the tumor microenvironment. We conducted high-throughput mRNA profiling (Affymetrix GeneChip Human Ge

NCBI GEO2026 · Non-coding RNA profiling by array · 6 samples

Polyglutamine expansion in Huntingtin (HTT) causes its aggregation and progressive loss of striatal neurons in Huntington’s disease (HD). HD is a mostly adult-onset neurodegenerative disorder with no disease-modifying therapies. Here we found that human striatal aging is associated with a global upregulation of genes involved in translation, including the translation and proteostasis regulator PPP

NCBI GEO2026 · Non-coding RNA profiling by array · 102 samples

We profiled extracellualr miRNAs derived from extracellular vessicles (EV) and whole serum collected from a cohort of women to identify potential miRNA bioamrkers that could be used to predict chlamydia reinfection risk.

NCBI GEO2026 · Non-coding RNA profiling by array · 6 samples

We have completed the Arraystar Mouse circRNA Array V2 analysis of the 6 samples that you submitted. Total RNA from each sample was quantified using the NanoDrop ND-1000. The sample preparation and microarray hybridization were performed based on the Arraystar’s standard protocols. Briefly, total RNAs were digested with Rnase R (Epicentre, Inc.) to remove linear RNAs and enrich circular RNAs. Then

NCBI GEO2026 · Non-coding RNA profiling by array · 6 samples

Polyglutamine expansion in Huntingtin (HTT) causes its aggregation and progressive loss of striatal neurons in Huntington’s disease (HD). HD is a mostly adult-onset neurodegenerative disorder with no disease-modifying therapies. Here we found that human striatal aging is associated with a global upregulation of genes involved in translation, including the translation and proteostasis regulator PPP

NCBI GEO2026 · Non-coding RNA profiling by array · 18 samples

Accurate assessment of breast cancer (BC) risk is critical to improve early detection strategies and patient prognosis. Our research group takes a comparative species approach to study BC risk by capitalizing on data from species with inherently low or high incidence of mammary cancer to supplement rare human samples. Circulating microRNAs (c-miRNAs) are a promising class of molecules that have th

NCBI GEO2026 · Non-coding RNA profiling by array · 4 samples

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection in young children, the elderly, and immunocompromised hosts, and no effective vaccine or therapy exists for infants. PIWIL4, a member of the PIWI protein family that interacts with PIWI-interacting RNAs (piRNAs), was found to be induced by RSV infection in airway epithelial cells. To investigate the rol

NCBI GEO2026 · Non-coding RNA profiling by array · 12 samples

Embryonal tumours with multilayered rosettes (ETMRs) are aggressive paediatric brain tumours driven in most cases by amplification of the chromosome 19 microRNA cluster (C19MC), which upregulates the oncogene MYCN. Whether MYCN dysregulation alone is sufficient to produce ETMR-like tumours, independent of the broader C19MC machinery, has not been tested. Here, we show that sustained MYCN expressio

NCBI GEO2026 · RNA sequencing · 24 samples

This SuperSeries is composed of the SubSeries listed below.

NCBI GEO2026 · Excel spreadsheet · 12 samples

Individualized outcome prediction classifiers were successfully constructed through expression profiling of a total of 800 human miRNAs in serum samples of 12 pregnant women (4 samples from severe preeclampsia pregnancies, 4 samples from mild preeclampsia pregnancies and 4 samples from healthy pregnancies)

NCBI GEO2026 · Non-coding RNA profiling by array · 5 samples

Periodontal homeostasis is maintained by a delicate balance between tissue regeneration and degradation, orchestrated through complex regulatory networks of cellular and molecular signaling. The delivery of microRNAs (miRNAs) by EVs serves as a crucial post-transcriptional regulatory mechanism, fine-tuning these signaling cascades. In this study, we identified significant candidates contained in t

NCBI GEO2026 · Excel spreadsheet · 10 samples

β-thalassemia is a group of bone marrow disorders characterized by defects in erythropoiesis. Circular RNAs (circRNAs) are functionally significant and hold tremendous potential as diagnostic biomarkers and therapeutic targets in numerous human diseases. Although the functional interplay between N6-methyladenosine (m6A) RNA modifications and circRNAs is becoming increasingly well understood, their

NCBI GEO2026 · Non-coding RNA profiling by array · 16 samples

We aimed to describe miRNA expression in extracellular vesicles

NCBI GEO2026 · Non-coding RNA profiling by array · 6 samples

Circular RNA microarray was performed to profile the circular RNA transcriptome of mouse MOVAS cells with or without benzo[a]pyrene (BaP) treatment. MOVAS cells were exposed to 10 μM BaP for 72 hours, and untreated MOVAS cells were used as control, with three biological replicates for each group (6 samples in total). Total RNA extracted from all samples was digested with RNase R to eliminate linea

NCBI GEO2026 · Non-coding RNA profiling by array · 9 samples

mouse lncRNA profiling cardiac tissue lncRNA/mRNA experssion profiling

NCBI GEO2026 · Non-coding RNA profiling by array · 6 samples

To verify the expression profile of long non-coding RNAs (lncRNAs) and mRNAs in cervical cancer, identify their clinical significance in HPV16-associated cervical cancer, and annotate the biological function of mRNAs.

NCBI GEO2026 · Non-coding RNA profiling by array · 41 samples

Bronchopulmonary dysplasia (BPD) is a major complication of preterm birth. This study aimed to identify circulating miRNA biomarkers in peripheral blood of preterm infants for early risk prediction of BPD. Peripheral blood was collected from 41 very low birth weight (VLBW) and extremely low birth weight (ELBW) preterm newborns (BPD+: n=20; BPD-: n=21) at days 10-14 of life. Total RNA was profiled